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Eli Chemical provides invaluable services to pharmaceutical and
research communities across Canada and around the world.
With strength in synthetic organic chemistry, analytical
chemistry and biochemistry, Eli Chemical is a solution provider
to the pharmaceutical, biotechnology, and academic institutions.
As well as Eli Chemical has been producing fine chemicals on a
custom basis for research and manufacture. We flexibly supply
from grams to tones of our products to meet the variant needs of
our customer. The challenge from molecule to market is to find
the fastest and most efficient way through; we are committed to
understanding the challenges of our partners and offering them
innovative solutions integral to their long-term success.
We are actively looking for new challenges and partners as we
expand our business and our presence in the international
pharmaceutical and biotechnology industries .Our objective
oriented approach has made us a perfect complement for
aggressive organizations looking to enhance their own drug
discovery and development programs.
Company Details
Company Information
Jeremy Chen
Title:
Vice President
Area of Responsibility:
Domestic Sales & Marketing, Export Sales & Marketing, Management Executive, Customer Service, Research/Development/Engineering, Manufacturing/Production/Operations, Administrative Services
Telephone:
(416) 630-6535
Fax:
(270) 386-4983
Email:
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Products
3-[(acetyloxy)-methyl]-7-amino-8-oxo-5-thia-1-azabicyclo [4.2.0]
7-act
MOLECULAR FORMULA : C12H13N5O5S2 (M.W. : 371.4)
DESCRIPTION White crystal powder
WATER Not more than 3.0%
SPECIFIC OPTICAL ROTATION (Anhydrous basis, ) -200 ~ -215
COLOR VALUE Not more than 80 at 250nm
HEAVY METALS Not more than 20ppm
IRON Not more than 40ppm
ASSAY Not less than 99.0%* *as anhydrous basis
Antibiotic Categoty
Key intermediate for cefriaxone
Name
7-Amino-3-[[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-1,2,4-trizin-
3-yl)- thio]methyl]-cephalosporanic a
intermediate for
cefriaxone
Ttz
Synonym TTZ,OHMMT
Formula C4H5N3O2S
Purity min 98.5%
Mp. min. 245 Celsius Weight loss max. 0.5%
Appearance
White Powder
Usage Ceftriaxone
Name
3-Mercapto-2-Methyl-5-oxo-6-Hydroxy-1,2,4-Triazine
intermediate for
Ceftriaxone
CAS NO:
58909-39-0
S-2-benzothiazoyl-2-amino-alpha-methoxyimino-4-thiazoleacetate
S-2-benzothiazoyl-2-amino-alpha-methoxyimino-4-thiazoleacetate
Synonym MAEM
AE-ESTER
Formula C13H10N4O2S3
CAS NO. 80756-85-0 Purity min 98.5%
Mp. 128-131 Celsius Weight loss max. 0.5%
Appearance
Light green yellow powder or alike Usage
Ceftriaxone,Cefotaxime,Ceftamet Pivoxil
Name
S-2-benzothiazoyl-2-amino-alpha-methoxyimino-4-thiazoleacetate
Intermediate for
Ceftriaxone,Cefotaxime,Ceftamet Pivoxil
CAS
80756-85-0
Atmaa
Synonym ATMAA,MTAA,AMTAA,MATAA
Formula C6H7N3O3S
CAS NO. 65872-41-5 Purity min 99%
Mp. min. 180 Celsius Weight loss max. 0.5%
Appearance
White Powder Usage Cephalosporin
Name
2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid
intermediate for
Cefotaxime, Ceftriaxone,Cefepime, Ceftiofur, Cefteram
CAS
65872-41-5
Maem
S-2-benzothiazoyl-2-amino-alpha-methoxyimino-4-thiazoleacetate
Synonym MAEM
AE-ESTER
Formula C13H10N4O2S3
CAS NO. 80756-85-0 Purity min 98.5%
Mp. 128-131 Celsius Weight loss max. 0.5%
Appearance
Light green yellow powder or alike Usage
Ceftriaxone,Cefotaxime,Ceftamet Pivoxil
Name
S-2-benzothiazoyl-2-amino-alpha-methoxyimino-4-thiazoleacetate
Intermediate for
Ceftriaxone,Cefotaxime,Ceftamet Pivoxil
CAS
80756-85-0
Hata
Specifications
Synonym HATA
Formula C5H5N3O3S
Purity min 99%
Mp. min 190 Celsius
Water max. 0.5%
Appearance
Yellow powder or alike Usage Cephalosporin
Name
2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid
intermediate for
Ceftazidim, Cefdinir
CAS NO.
66338-96-3
Ehata
Specifications
Synonym EHATA
Formula C7H9N3O3S
Purity min 98%
Mp. min 183 Celsius
Weight loss max. 0.5%
Appearance
Yellow powder or alike
Usage Cephalosporin
Name
Ethyl 2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetate
intermediate for
cefdinir, cefixime and ceftazidime
CAS_No.
. 64485-82-1
Ate
Specifications
Synonym ATE
Formula C8H11N3O3S
Purity min 98%
Mp. min 155 Celsius
Weight loss max. 0.5%
Appearance
Yellow powder or alike Usage Cephalosporin
Name
Ethyl 2-(2-aminothiazole-4-yl)-2-methoxyiminoacetate
intermediate for
Ceftriaxone and Cefotaxime
CAS NO.
. 64485-88-7
Ata
Brand Name
(2-Aminothiazole-4-yl)acetic acid
Specifications
Synonym ATA
Formula C5H6N2O2S
Purity min 98%
Mp. min 129 Celsius
Water max. 0.5%
Appearance
White Powder Usage Cefotiam
intermediate for
Cefotiam
CAS NO.
29676-71-9
Taem
Specifications
Synonym TAEM
Formula C20H22N4O4S3
Purity min 98%
Mp. min. 135 Celsius
Weight loss max. 0.5%
Appeaeance
Light green yellow powder Usage Ceftazidime Sodium
Name
S-2-benzothiazoyl-(Z)-2-(1-ter-butoxycanbonyl-1-
methylethoxyimino)-4-thiazoleacetate
intermediate for
Ceftazidime and Aztreonam.
CAS NO.
89604-92-2
Attba
Specifications
Synonym ATTBA
Formula C13H19N3O5S
Purity min 98%
Mp. mix 178 Celsius
Weight loss max. 0.5%
Appearance
White Powder
Usage Ceftazidime Sodium
Name
(Z)-2-amino-alpha-[1-(tert-butoxycarbonyl)]-1-1-
methylethoxyimino-4-thiazoleacetic acid
intermediate for
Ceftazidime and Aztreonam
CAS NO.
86299-47-0
Eata
Brand Name
Ethyl 2-amino-4-thiazoleacetate
Specifications
Synonym EATA
Formula C7H10N2O2S
Assay min 95%
Mp. min 87 Celsius
Weight loss max. 0.5%
Appearance
light yellow powder
Usage Cefitiam
intermediate for
Cefitiam
CAS NO.
53266-94-7
Mbt
Name
2-Mercaptobenzothiazolyl (Z)-2-(2-Aminothiazole-4-yl)-2- (Tert-
Butoxycarbonyl) -Methoxyimino Acetate
intermediate for
Cefixime
Cmoba
Name
4-Chloro-(Z)-2-Methoxycarbonyl-Methoxyimino-3-Oxobutanoic Acid
intermediate for
Cefixime
Amma
Name
(Z)-2-(2-Aminothiazole-4-yl)-2-Methoxycarbonyl-Methoxyimino
Acetic Acid
intermediate for
Cefixime
D-a-dihydro Phenyl Glycine
DHG
Name
intermediate
Cefroxadine.
D-a-dihydro Phenyl Glycine Dane Salt
intermediate for
Cefradine, Cefroxadine
2-methyl-5-mercapto-1,3,4-thiadiazole
MMTD
Name
intermediate for
Cefazolin, Cefamandole
1,2,3,4-tetrazolyl-1- Acetic Acid
TAA
Name
intermediate for
Cefazolin, Ceftezole
Sin-methoxyimino Furanyl Acetic Acid Ammonium Salt
SMIA
Name
intermediate for
Cefuroxime Axetil
N-ethyl-(2,3-dioxo-n-piperazinil) Carbonyl Chloride
EDP-Cl
Name
intermediate for
Piperaciline, Cefoperazone
Ho-epcp
Advantages
a-{[(4-Ethyl-2,3-Dioxo-1-Piperazinyl)Carbonyl] Amino}-4-
Hydroxy-Benzene Acetic Acid
intermediate for
Cefoperazone.
5-mercapto-1-methyl-1,2,3,4-tetrazole
MMTZ
Name
intermediate for
Cefoperazone, Cefteram, Cefamandole, Cefotetan
2-(2-mercapto-4-methyl-1,3-thiazole-5-yl) Acetic Acid
MMTA
Advantages
The side chain of
Nmane
intermediate for
Cefodizim
1-sulfonylmethyl-5-mercaptotetrazole Disodium Salt
SMT
Advantages
Name
intermediate for
Cefonicid
Ceftriaxone Sodium
Specifications
APPEARANCE
White to slightly yellowish crystalline powder
ASSAY
795g/mg min (Ceftriaxone),
96.0~102.0% (Ceftriaxone Sodium ;as anhydrous basis)
MOISTURE 8.0 ~11.0%
pH
6 - 8 (1% aq sol.)
HEAVY METALS
20ppm max
OPTICAL ROTATION
-153?~ -170?
FORMULA
C18H16N8O7S3.5H2O
CAS NO.
104376-79-6
Cefotaxime Sodium
Specifications
MOLECULAR FORMULA : C16H16N5NaO7S2 (M.W.: 477.46
DESCRIPTION White to yellowish crystalline powder
SPECIFIC OPTICAL ROTATION () Between+58 and +64
BACTERIAL ENDOTOXINS Not more than 0.20 EU/mg
STERILITY By U.S.P 24
pH Between 4.5 and 6.5(1 in. 10)
WATER Not more than 6.0%
ASSAY Not less than 916 and Not more than 964 / (as anhydrous
basis)
IDENTIFICATION HPLC, Na
CLARITY AND COLOR OF SOLUTION 1) Clear
2) Absorbance : Not more than 0.20(430nm)
LOSS ON DRYING Not more than 3.0%
PARTICULATE MATTER By U.S.P 24
(Microscopic Method Particle Count)
10 Not more than 3,000 Particles
25 Not more than 300 Particles
PURITY 1)Each impurity : Not more than 1.0 %
2)Sum of all impurities :Not more than 3.0 %
Advantages
Cefotaxime generally is less active in vitro against
susceptible staphylococci than first generation cephalosporins
but has an expanded spectrum of activity against gram-negative
bacteria compared with first and second generation
cephalosporins
Cefepime
CAS
88040-23-7
Cefixime
CAS
79350-37-1
Cefazolin Sodium
Cefoperazone Sodium
Ceftazidime
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