Dalton Pharma Services
Historical Background
Dalton Chemical Laboratories Inc., was initally established to
bring the benefits of modern instrumentation and chemical
expertise to the Chemistry Department at York University. Over
the years, Dalton has been providing advice and consultation to many chemical, pharmaceutical and analytical establishments across North American chemical, pharmaceutical and biotechnology industries. We have grown into a company that has expertise in synthetic organic and peptide chemistry, process development, scale-up and cGMP manufacturing of active pharmaceutical ingredients.
Dalton has been producing fine chemicals on a custom basis for
research and for chemical supply houses over the eighteen years
(viz. Sigma, Aldrich, Fluka, ICN, BDH). As part of our business
effort, we have identified and supplied many new reagents for
biological and commercial synthetic purposes. We have
specialized in oligo-RNA and DNA synthesis as it has been a
unique opportunity for low-volume, high value-added fine
chemical production with strong growth potential. More recently we have identified pharmaceutical impurity and analog synthesis and drug discovery as areas of growing demand. For this reason we have developed our contract research capabilities. In 1996
Dalton established a cGMP manufacturing operation for production
of Bulk Pharmaceuticals as we anticipate strong growth in this
portion of the business.
Company Background
Incorporated: April 1987
Type of Business:
Custom Synthetic Chemistry, Fine Chemicals Production, Research
and Development by Contract, cGMP Production of Pharmaceuticals,
Analytical Methods Development, oligo nucleotide production,
RNA/DNA and thioates.
Facilities:
42,000 sq ft facility: Synthetic chemistry laboratory space, fully climate controlled; cGMP manufacturing suites, 38 linear ft.
of fume hood space; cryogenics; separate shipping/receiving
area; flammable storage facilities; walk in cold rooms; licensed waste storage and handling facilities; library and writing area facilities; conference rooms/staff lounge.
Services:
Custom synthesis of organic of organometallic compounds,
milligrams to kilograms, and of specific isotopically labelled
substances or standards;
Consultation in relation to organic methods development and
fine-tuning of synthetic procedures at the bench level for
chemical manufacture.
Contract Research and Development;
Structure elucidation of organic unknowns;
Separation and analysis of organic mixtures, including GC/MS,
HPLC, including semiprep. HPLC, capillary GC, capillary
electrophoresis, UV, IR;
High field NMR and analysis of spectra;
Custom synthesis of high purity DNA/RNA oligonucleotides,
including biotin, thioates and fluorescent labelled oligos.
Sales Organization:
Dalton sells chemical products in bulk to distributors and
catalogue sales organizations under OEM arrangements. Dalton also sells directly to end users via telemarketing and direct mail programs.
Production Laboratory, Equipment and Facilities:
DCL is capable of producing fine chemicals in multi-kilo batches using 20L and 30L glass reactors. A full range of lab scale equipment is available, including Parr hydrogenation (500ml) up to 80psi, liquid ammonia chemistries, inert atmosphere and high vacuum capabilities.
Dalton operates a cGMP production area in one of our synthetic
laboratories, capable of producing multi-gram quantities of
Active Pharmaceutical Ingredients. Future expansion plans
include a larger cGMP manufacturing facility to provide
larger scales of drug grade materials.
Business Development
Dalton is seeking to increase our contract research and custom
synthesis activities. The custom synthesis opportunities we
are actively developing will be for pharmaceutical, biopharmaceutical and biological products, both cGMP and non-cGMP. We will also
develop new and innovative molecules for biological applications,
both under contract as well as for direct sales and license.
Dalton is looking for research partners and organizations that
will make use of Dalton expertise to further develop research
objectives. Dalton is looking for pharmaceutical and
biopharmaceutical contacts looking for a contract synthesis
laboratory for the synthesis of small molecules.
Company Details
Year Established:
1986
Total Sales ($CDN):
$1,000,000 - $5,000,000
Number of Employees:
83
Company Information
Peter Pekos
Title:
President
Area of Responsibility:
Management Executive, Domestic Sales & Marketing, Export Sales & Marketing
Telephone:
(416) 661-2102
Fax:
(416) 661-2108
Email:
Click Here
Natalie Lazarowych
Title:
Director
Area of Responsibility:
Research/Development/Engineering, Manufacturing/Production/Operations
Telephone:
(416) 661-2102
Fax:
(416) 661-2108
Email:
Click Here
Products
Organic Chemicals Nes
Acetonitrile
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Cyclohexane
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Cyclohexene
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Malic Acid
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Precious Metal Compds, Organic Or Inorg Nes
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Sulphamethoxazole, In Bulk
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Laboratory Reagents
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Ethylene Dichloride
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Cycl(anic)(enic)(oterpenic) Alcohol&deriv Nes
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Ketone & Quinone Function Compound Deriv
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N,N-dimethylformamide
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Pyridine
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Fine Chemicals
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Botanical Reference Standards
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Environmental Reference Standards
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Custom Peptides
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Custom Antibodies
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Custom Organic Synthesis
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Active Pharmaceutical Ingredients
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Small Molecule
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Chiral Chemistry
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Services
Contract Research
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Contract Analysis
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Contract Consulting
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Cgmp Manufacturing
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Sterile Filling
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Biotechnology
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